:root {
    --brand-color: #005878;

    --palette-primary-green: #60b038;
    --palette-medium-green: #68b838;
    --palette-dark-teal: #005878;
    --palette-mint-white: #eef5f4;
    --palette-soft-teal: #6aa3b0;
    --palette-pale-green: #d2ebc4;
    --palette-muted-teal: #4d8794;
    --palette-sage-green: #7aaa58;
    --palette-light-cyan: #c5dde4;

    --kme1-bg: #edf6c8;
    --kme1-text: #4a6318;
    --kme1-border: #a8d647;
    --kme1-track: #a8d647;

    --kme2-bg: #c5e8a5;
    --kme2-text: #1e4620;
    --kme2-border: #60b038;
    --kme2-track: #60b038;

    --kme3-bg: #cfe9f0;
    --kme3-text: #003648;
    --kme3-border: #005878;
    --kme3-track: #005878;

    --kme-bg: #fff0c2;
    --kme-text: #7c4a03;
    --kme-border: #e6a817;
    --kme-track: #e6a817;
}

.skip-link {
    position: absolute;
    left: -9999px;
    top: auto;
    width: 1px;
    height: 1px;
    overflow: hidden;
    z-index: 2000;
    padding: 0.75rem 1rem;
    background: #ffffff;
    color: var(--brand-color);
    font-weight: 600;
    text-decoration: none;
    border: 2px solid var(--brand-color);
    border-radius: 0.375rem;
}

.skip-link:focus {
    position: fixed;
    left: 1rem;
    top: 1rem;
    width: auto;
    height: auto;
    overflow: visible;
}

.navbar {
    background: linear-gradient(to right, var(--palette-dark-teal), var(--palette-primary-green)) !important;
    padding: 0.8rem 0;
}

.navbar-nav .nav-item {
    margin-right: 1.5rem;
}

.navbar-nav .nav-link {
    color: #fefefd !important;
    font-weight: bold;
}

.navbar-nav .nav-link:hover {
    color: #ffffff !important;
}

.navbar-nav .nav-link.active {
    color: #ffffff !important;
    background-color: rgba(0, 0, 0, 0.25);
    border-radius: 0.375rem;
}

.navbar-search-wrap {
    width: 300px;
}

.navbar-search-form {
    width: 100%;
}

.navbar-search-examples {
    display: flex;
    gap: 0.5rem;
    margin-top: 0.35rem;
    flex-wrap: wrap;
}

.navbar-search-example {
    font-size: 0.7rem;
    line-height: 1.2;
    padding: 0.15rem 0.5rem;
    border: 1px solid rgba(255, 255, 255, 0.55);
    border-radius: 0.25rem;
    background: rgba(255, 255, 255, 0.12);
    color: #fff;
    cursor: pointer;
}

.navbar-search-example:hover:not(:disabled) {
    background: rgba(255, 255, 255, 0.22);
    color: #fff;
}

.navbar-search-example:disabled {
    opacity: 0.45;
    cursor: not-allowed;
}

.search-border-brand {
    border-color: var(--palette-dark-teal);
}

.search-button {
    background-color: var(--palette-dark-teal);
    border-color: var(--palette-dark-teal);
}

.search-button .fa-search {
    color: white;
}

.bg-brand {
    background-color: var(--brand-color) !important;
    color: white !important;
}

.btn-brand {
    background-color: var(--brand-color);
    color: white;
    border: none;
}

.btn-brand:hover {
    background-color: #004868;
    color: white;
}

.btn-outline-brand {
    border-color: var(--brand-color);
    color: var(--brand-color);
}

.btn-outline-brand:hover {
    background-color: var(--brand-color);
    color: white;
}

.custom-card {
    border: 1px solid #dee2e6;
    border-radius: 8px;
    padding: 20px;
    background: #fff;
    box-shadow: 0 0.125rem 0.25rem rgba(0, 0, 0, 0.075);
}

.page-layout {
    width: 100%;
}

.sidebar {
    flex: 0 0 130px;
    width: 130px;
    min-width: 130px;
    background-color: #f8f9fa;
    padding: 20px;
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: flex-start;
}

.sidebar-logo {
    max-width: 100%;
    height: auto;
}

.main-content-wrapper {
    flex: 1;
    min-width: 0;
}

.home-intro {
    text-align: justify;
}

.home-logo {
    max-width: 320px;
}

.sequence-viewer-container {
    min-height: 200px;
}

.button {
    display: inline-block;
    padding: 0.375rem 0.75rem;
    background-color: var(--brand-color);
    color: white;
    text-decoration: none;
    border-radius: 0.375rem;
}

.button:hover {
    background-color: #004868;
    color: white;
}

.form-spaced {
    margin-top: 16px;
}

.import-errors {
    color: #c00;
    margin-top: 16px;
}

.site-footer {
    margin-top: 1.5rem;
    padding: 0 1rem 1rem;
    display: flex;
    justify-content: center;
}

.site-footer-inner {
    display: inline-flex;
    align-items: center;
    gap: 0.6rem;
    padding: 0.35rem 0.85rem;
    font-size: 0.75rem;
    line-height: 1.2;
    color: var(--palette-muted-teal);
    background: linear-gradient(135deg, #fff 0%, var(--palette-mint-white) 100%);
    border: 1px solid var(--palette-light-cyan);
    border-radius: 999px;
    box-shadow: 0 1px 6px rgba(0, 88, 120, 0.08);
}

.site-footer-org {
    font-weight: 600;
    letter-spacing: 0.02em;
    color: var(--palette-dark-teal);
    white-space: nowrap;
}

.site-footer-sep {
    flex-shrink: 0;
    width: 1px;
    height: 0.75rem;
    background: var(--palette-soft-teal);
    opacity: 0.7;
}

.site-footer-copy {
    font-size: inherit;
    font-weight: 500;
    color: var(--palette-primary-green);
    white-space: nowrap;
}

.site-footer-contact {
    font-weight: 500;
    color: var(--palette-dark-teal);
    text-decoration: none;
    white-space: nowrap;
}

.site-footer-contact:hover,
.site-footer-contact:focus {
    color: var(--palette-primary-green);
    text-decoration: underline;
}

.pagination-toolbar {
    display: flex;
    flex-wrap: wrap;
    justify-content: space-between;
    align-items: center;
    gap: 0.75rem;
}

.pagination-toolbar-summary {
    color: #6c757d;
    font-size: 0.875rem;
    line-height: 1.4;
}

.pagination-toolbar-nav {
    max-width: 100%;
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
}

.pagination-toolbar-nav .pagination {
    flex-wrap: nowrap;
}

.pagination-toolbar-end {
    display: flex;
    justify-content: flex-end;
    max-width: 100%;
    overflow-x: auto;
    -webkit-overflow-scrolling: touch;
}

@media (max-width: 991.98px) {
    .page-layout {
        flex-direction: column;
    }

    .sidebar {
        flex: 0 0 auto;
        width: 100%;
        min-width: 0;
        padding: 0.65rem 1rem;
        flex-direction: row;
        justify-content: center;
        border-bottom: 1px solid var(--palette-light-cyan);
    }

    .sidebar-logo {
        max-height: 2.75rem;
        width: auto;
    }

    .navbar {
        padding: 0.55rem 0;
        margin-bottom: 1rem !important;
    }

    .navbar-nav {
        width: 100%;
        padding-top: 0.35rem;
    }

    .navbar-nav .nav-item {
        margin-right: 0;
    }

    .navbar-nav .nav-link {
        padding-top: 0.55rem;
        padding-bottom: 0.55rem;
        padding-left: 0.65rem;
        padding-right: 0.65rem;
        color: #ffffff !important;
    }

    .navbar-nav .nav-link.active {
        color: #ffffff !important;
        background-color: rgba(0, 0, 0, 0.3);
    }

    .navbar-nav .nav-link:hover {
        color: #ffffff !important;
        background-color: rgba(0, 0, 0, 0.15);
        border-radius: 0.375rem;
    }

    .navbar-toggler {
        border-color: rgba(255, 255, 255, 0.75);
    }

    .navbar-toggler:focus {
        box-shadow: 0 0 0 0.2rem rgba(255, 255, 255, 0.35);
    }

    .navbar-search-wrap {
        width: 100%;
        max-width: none;
        margin-left: 0 !important;
        margin-top: 0.75rem;
    }

    .navbar-search-form {
        width: 100%;
        max-width: none;
    }

    .navbar-collapse {
        padding-bottom: 0.35rem;
    }
}

@media (max-width: 767.98px) {
    .custom-card {
        padding: 1rem;
        border-radius: 0.5rem;
    }

    .container-fluid.px-3 {
        padding-left: 0.85rem !important;
        padding-right: 0.85rem !important;
    }

    h1,
    h2 {
        font-size: 1.35rem;
        line-height: 1.3;
    }

    h3 {
        font-size: 1.125rem;
    }

    .pagination-toolbar {
        flex-direction: column;
        align-items: stretch;
    }

    .pagination-toolbar-end {
        justify-content: flex-start;
    }

    .site-footer-inner {
        flex-wrap: wrap;
        justify-content: center;
        row-gap: 0.25rem;
        max-width: 100%;
        border-radius: 0.75rem;
        text-align: center;
    }

    .site-footer-org,
    .site-footer-copy,
    .site-footer-contact {
        white-space: normal;
    }

    .site-footer-sep {
        display: none;
    }
}

@media (max-width: 575.98px) {
    .home-logo {
        max-width: 220px;
    }
}

.back-to-top {
    position: fixed;
    right: 1.25rem;
    bottom: 1.25rem;
    z-index: 1030;
    display: inline-flex;
    align-items: center;
    justify-content: center;
    width: 2.75rem;
    height: 2.75rem;
    border: 1px solid var(--palette-pale-green);
    border-radius: 999px;
    background: var(--palette-dark-teal);
    color: #fff;
    box-shadow: 0 4px 12px rgba(0, 88, 120, 0.25);
    cursor: pointer;
    transition: background-color 0.2s ease, transform 0.2s ease, opacity 0.2s ease;
}

.back-to-top:hover,
.back-to-top:focus {
    background: var(--palette-primary-green);
    color: #fff;
    transform: translateY(-2px);
    outline: none;
}

.back-to-top[hidden] {
    display: none;
}

.kme-label {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    box-sizing: border-box;
    padding: 0.25rem 0.55rem;
    min-height: 1.5rem;
    border-radius: 0.375rem;
    font-size: 0.75rem;
    font-weight: 600;
    line-height: 1;
    white-space: nowrap;
    border: 1px solid transparent;
    text-align: center;
    vertical-align: middle;
}

.kme-label-kme1 {
    background-color: var(--kme1-bg);
    color: var(--kme1-text);
    border-color: var(--kme1-border);
}

.kme-label-kme2 {
    background-color: var(--kme2-bg);
    color: var(--kme2-text);
    border-color: var(--kme2-border);
}

.kme-label-kme3 {
    background-color: var(--kme3-bg);
    color: var(--kme3-text);
    border-color: var(--kme3-border);
}

.kme-label-kme,
.kme-label-unknown,
.kme-label-other,
.kme-label[class*="kme-label-"]:not(.kme-label-kme1):not(.kme-label-kme2):not(.kme-label-kme3):not(.kme-label-kme) {
    background-color: var(--kme-bg);
    color: var(--kme-text);
    border-color: var(--kme-border);
}

@media (max-width: 767.98px) {
    .back-to-top {
        right: 1rem;
        bottom: 1rem;
        width: 2.5rem;
        height: 2.5rem;
    }
}